butabarbital will lower the extent or effect of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.diazepam will enhance the degree or outcome of lonafarnib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. If coadministration of lonafarnib (a sensitive CYP3A substrate) with… Read More